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    Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/101821


    Title: Stem Cell Therapy for Treatment of Ocular Disorders
    Authors: 樋口亞紺;Kumar, S. Suresh;Umezawa, Akihiro;Munusamy, Murugan A.;Alarfaj, Abdullah A.;Murugan, Kadarkarai;Higuchi, Akon;Mok, Pooi-Ling;Syed, Sakinah;Sivan, Padma Priya;Hamat, Rukman Awang
    Contributors: 工學院化學工程與材料工程學系
    Keywords: Colleges & universities;Cytokines;Diabetes;Diabetic retinopathy;Eye diseases;Gene expression;Genetic aspects;Genetic transcription;Grants;Growth factors;Hypoxia;Ionizing radiation;Medical research;Medicine, Experimental;Ophthalmology;Retina;Review;Science;Stem cells;Transplantation;Zoology
    Date: 2016-01-01
    Issue Date: 2026-04-21 14:46:39 (UTC+8)
    Publisher: Hindawi Publishing Corporation;Cairo, Egypt: Hindawi Publishing Corporation
    Abstract: 摘要: Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow conventional treatments have shifted search to a new form of therapy using stem cells. Stem cell progenitors play a major role in replenishing degenerated cells despite being present in low quantity and quiescence in our body. Unlike other tissues and cells, regeneration of new optic cells responsible for visual function is rarely observed. Understanding the transcription factors and genes responsible for optic cells development will assist scientists in formulating a strategy to activate and direct stem cells renewal and differentiation. We review the processes of human eye development and address the strategies that have been exploited in an effort to regain visual function in the preclinical and clinical state. The update of clinical findings of patients receiving stem cell treatment is also presented.
    其他題名: Stem Cells Int
    出版者: Cairo, Egypt: Hindawi Publishing Corporation
    出版日期: 2016-01-01
    出處: Stem Cells International, 2016-01, Vol.2016 (2016), p.1-18
    資源來源: Chinese Electronic Periodical Services (CEPS)
    版權: Copyright © 2016 Padma Priya Sivan et al.
    版權: COPYRIGHT 2016 John Wiley & Sons, Inc.
    版權: Copyright © 2016 Padma Priya Sivan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    版權: Copyright © 2016 Padma Priya Sivan et al. 2016
    識別號: ISSN: 1687-966X
    識別號: ISSN: 1687-9678
    識別號: EISSN: 1687-9678
    識別號: DOI: 10.1155/2016/8304879
    識別號: PMID: 27293447
    Appears in Collections:[Department of Chemical and Materials Engineering] journal & Dissertation

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