Surface PEGylation of silver nanoparticles: Kinetics of simultaneous surface dissolution and molecular desorption

NCUIR > Engineering College > Department of Chemical and Materials Engineering > journal & Dissertation > Item 987654321/101994

Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/101994

Title:	Surface PEGylation of silver nanoparticles: Kinetics of simultaneous surface dissolution and molecular desorption
Authors:	王孝方;Chang, Wei-Chang;Tai, Jui-Ting;Wang, Hsiao-Fang;Ho, Rong-Ming;Hsiao, Ta-Chih;Tsai, De-Hao
Contributors:	工學院化學工程與材料工程學系
Keywords:	adsorption;desorption;gases;Interface Components: Nanops, Colloids, Emulsions, Surfactants, Proteins, Polymers;molecular weight;nanoparticles;nanosilver;polyethylene glycol;protons;prototypes;silver;thiols
Date:	2016-09-27
Issue Date:	2026-04-21 14:55:22 (UTC+8)
Publisher:	American Chemical Society;United States: American Chemical Society
Abstract:	摘要： A quantitative study of the stability of silver nanoparticles (AgNPs) conjugated with thiolated polyethylene glycol (SH-PEG) was conducted using gas-phase ion-mobility and mass analyses. The extents of aggregation and surface dissolution of AgNPs, as well as the amount of SH-PEG adsorption and desorption, were able to be characterized simultaneously for the kinetic study. The results show that the SH-PEG with a molecular mass of 6 kg/mol (SH-PEG6K) was able to adsorb to the surface of AgNP to form PEG6K-HS-AgNP conjugates, with the maximum surface adsorbate density of ∼0.10 nm–2. The equilibrium binding constant for SH-PEG6K on AgNPs was calculated as ∼(4.4 ± 0.9) × 105 L/mol, suggesting a strong affinity due to thiol bonding to the AgNP surface. The formation of SH-PEG6K corona prevented PEG6K-HS-AgNP conjugates from aggregation under the acidic environment (pH 1.5), but dissolution of core AgNPs occurred following a first-order reaction. The rate constant of Ag dissolution from PEG6K-HS-AgNP was independent of the starting surface packing density of SH-PEG6K on AgNP (σ0), indicating that the interactions of H+ with core AgNP were not interfered by the presence of SH-PEG6K corona. The surface packing density of SH-PEG6K decreased simultaneously following a first-order reaction, and the desorption rate constant of SH-PEG6K from the conjugates was proportional to σ0. Our work presents the first quantitative study to illustrate the complex mechanism that involves simultaneous aggregation and dissolution of core AgNPs in combination with adsorption and desorption of SH-PEG. This work also provides a prototype method of coupled experimental scheme to quantify the change of particle mass versus the corresponding surface density of functional molecular species on nanoparticles. 其他題名： Langmuir 出版者： United States: American Chemical Society 出版日期： 2016-09-27 出處： Langmuir, 2016-09, Vol.32 (38), p.9807-9815 資源來源： American Chemical Society Journals 版權： Copyright © 2016 American Chemical Society 識別號： ISSN: 0743-7463 識別號： ISSN: 1520-5827 識別號： EISSN: 1520-5827 識別號： DOI: 10.1021/acs.langmuir.6b02338 識別號： PMID: 27578534
Appears in Collections:	[Department of Chemical and Materials Engineering] journal & Dissertation

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	24	View/Open

社群 sharing

Loading...