Estimation of the benchmark dose for right-censored lifetime data

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Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/102135

Title:	Estimation of the benchmark dose for right-censored lifetime data
Authors:	陳玉英;Chen, Yuh-Ing;Lin, Wen-Ming
Contributors:	太空科學與科技研究中心
Keywords:	62-07;Benchmark dose;Benchmarking;Computation;Computer simulation;Confidence limits;Estimating;Extra risk;Hazards;Monte Carlo methods;Monte Carlo simulation;Proportional hazards model;Receiving;Right-censored lifetime;Weibull extension distribution
Date:	2015-01-01
Issue Date:	2026-04-23 11:03:22 (UTC+8)
Publisher:	Taylor and Francis Ltd.;Philadelphia: Taylor & Francis
Abstract:	摘要： In this paper, we consider estimating the benchmark dose in a dose-response study with right-censored lifetime data, where the benchmark dose is the dose corresponding to a specific benchmark response, which is related to the probability that the lifetime of a subject receiving the dose is too short. Under the Cox or Weibull extension proportional hazards model, simultaneous lower confidence limits on the benchmark dose are developed. We further conduct a Monte Carlo study to investigate the performance of the proposed lower confidence limits. Finally, a real dataset is illustrated to demonstrate the application of the proposed procedures. 出版者： Philadelphia: Taylor & Francis 出版日期： 2015-07-03 出處： Communications in statistics. Simulation and computation, 2015-07, Vol.44 (6), p.1514-1531 版權： Copyright © Taylor & Francis Group, LLC 2015 版權： Copyright © Taylor & Francis Group, LLC 識別號： ISSN: 0361-0918 識別號： EISSN: 1532-4141 識別號： DOI: 10.1080/03610918.2013.813038
Appears in Collections:	[CENTER FOR ASTRONAUTICAL PHYSICS AND ENGINEERING (CAPE)] journal & Dissertation

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