Oxford University Press;Oxford: Oxford University Press
摘要:
摘要： Background The soil-dwelling pathogen Burkholderia pseudomallei is the cause of melioidosis. In this study, the geographical and temporal distributions of predominant molecular patterns occurring in clinical and environmental isolates of B. pseudomallei were characterised. Methods A collection of 194 human and 59 soil B. pseudomallei isolates obtained in Taiwan were analysed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Results Five predominant PFGE types (VI, X, XI, XV and XVI) among human isolates were identified between 2004 and 2010. Among them, types VI, X and XI correspond to ST58, and types XV and XVI correspond to ST99. The distribution of B. pseudomallei with distinct PFGE or MLST types was clustered in different towns in southern Taiwan. Clusters of B. pseudomallei have successively appeared in the town of Jiading, which is located in the Er-Ren River Basin of southern Taiwan. Conclusions Burkholderia pseudomallei isolates were geographically and temporally clustered in Taiwan. This finding supports the contention that the Er-Ren River Basin now constitutes the highest risk area for melioidosis in Taiwan. 其他題名： Trans R Soc Trop Med Hyg 出版者： Oxford: Oxford University Press 出版日期： 2013-03-01 出處： Transactions of the Royal Society of Tropical Medicine and Hygiene, 2013-03, Vol.107 (3), p.165-169 版權： Royal Society of Tropical Medicine and Hygiene 2013. All rights reserved. For Permissions, please email: journals.permissionsoup.com 2013 版權： 2014 INIST-CNRS 識別號： ISSN: 0035-9203 識別號： ISSN: 1878-3503 識別號： EISSN: 1878-3503 識別號： DOI: 10.1093/trstmh/trs093 識別號： PMID: 23355636 識別號： CODEN: TRSTAZ
