Blood neutrophil-to-lymphocyte ratio correlates with tumor size in patients with differentiated thyroid cancer

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題名:	Blood neutrophil-to-lymphocyte ratio correlates with tumor size in patients with differentiated thyroid cancer
作者:	許藝瓊;Liu, Chien-Liang;Lee, Jie-Jen;Liu, Tsang-Pai;Chang, Yuan-Ching;Hsu, Yi-Chiung;Cheng, Shih-Ping
貢獻者:	生醫理工學院生醫科學與工程學系
關鍵詞:	Adenocarcinoma, Follicular - pathology;Adenocarcinoma, Follicular - surgery;Adenocarcinoma, Papillary - pathology;Adenocarcinoma, Papillary - surgery;Adult;Case-Control Studies;Cell Count;Female;Humans;inflammation;Lymphocytes - metabolism;Male;Middle Aged;Multivariate Analysis;Neoplasm Recurrence, Local;neutrophil-to-lymphocyte ratio;Neutrophils - metabolism;Risk Assessment;thyroid cancer;Thyroid Neoplasms - pathology;Thyroid Neoplasms - surgery;Thyroidectomy
日期:	2013-04-01
上傳時間:	2026-04-23 11:15:15 (UTC+8)
出版者:	Hoboken: Wiley Subscription Services, Inc., A Wiley Company
摘要:	摘要： Background and Objectives Inflammation has been implicated in the initiation and progression of thyroid cancer. Neutrophil‐to‐lymphocyte ratio (NLR) is a simple index of systemic inflammatory response, and has been shown to be a prognostic indicator in some types of cancer. The aim of this study was to examine the relationship between NLR and clinicopathological features in patients with differentiated thyroid cancer. Methods Total white blood cell and differential counts of 159 patients with differentiated thyroid cancer were compared to those of 318 age‐ and sex‐matched controls undergoing thyroidectomy for benign thyroid nodules. Clinicopathological variables, stratified by NLR tertiles, were analyzed. Results There was no difference in NLR between patients having benign and malignant thyroid nodules (P = 0.293). Cancer patients in the higher NLR tertile had significantly larger tumor size (P = 0.004). Higher NLR was observed in patients with high American Thyroid Association (ATA) risk of recurrence. Conclusions High preoperative NLR was associated with increased tumor size and high ATA risk of recurrence in patients with differentiated thyroid cancer. J. Surg. Oncol. 2013;107:493–497. © 2012 Wiley Periodicals, Inc. 其他題名： J. Surg. Oncol 出版者： Hoboken: Wiley Subscription Services, Inc., A Wiley Company 出版日期： 2013-04-01 出處： Journal of surgical oncology, 2013-04, Vol.107 (5), p.493-497 資源來源： Wiley Online Library Journals AutoHoldings 版權： Copyright © 2012 Wiley Periodicals, Inc. 識別號： ISSN: 0022-4790 識別號： ISSN: 1096-9098 識別號： EISSN: 1096-9098 識別號： DOI: 10.1002/jso.23270 識別號： PMID: 22996403
顯示於類別:	[生醫科學與工程學系] 期刊論文

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