摘要： [Display omitted] •Hand tremor in Parkinson patients was detected by a laser line triangulation measurement method.•Significant correlations between clinical manifestations and hand tremor frequency were found.•The measurement is a novel method on early detection of movement disorders in Parkinson patients. Detection of hand tremor for evaluating and diagnosing early stage of Parkinson’s disease (PD) remains a challenge. The purpose of this study was to correlate hand tremors analyzed by a non-invasive method with clinical manifestations among patients with PD. Four different modes of tremor detection in patients with PD were detected individually using a laser line triangulation measurement (LLTM) method and off-line analyzed. The results showed a significant correlation between age at disease onset and tremor frequency obtained from the left hand and from the non-dominant hand. Furthermore, there was a significant positive correlation between disease duration and tremor frequency obtained from the left hand and from the non-dominant hand using different detection modes. We conclude that the laser line triangulation measurement is a non-invasive, non-contact, portable, easy-to-use and low cost method that can detect tremor early in the course of patients diagnosed with PD. 出版者： Elsevier Ltd 出版日期： 2016-02-01 出處： Measurement : journal of the International Measurement Confederation, 2016-02, Vol.79, p.20-28 版權： 2015 Elsevier Ltd 識別號： ISSN: 0263-2241 識別號： EISSN: 1873-412X 識別號： DOI: 10.1016/j.measurement.2015.10.028
