Diameter-sensitive biocompatibility of anodic TiO2 nanotubes treated with supercritical CO2 fluid

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題名:	Diameter-sensitive biocompatibility of anodic TiO2 nanotubes treated with supercritical CO2 fluid
作者:	李勝偉;Lan, Ming-Ying;Liu, Chia-Pei;Huang, Her-Hsiung;Chang, Jeng-Kuei;Lee, Sheng-Wei
貢獻者:	工學院材料科學與工程研究所
關鍵詞:	Carbon dioxide;Chemistry and Materials Science;Irradiation;Materials Science;Molecular Medicine;Nano Express;Nanochemistry;Nanoscale Science and Technology;Nanotechnology;Nanotechnology and Microengineering;Photooxidation;Titanium dioxide;Ultraviolet radiation
日期:	2013-01-01
上傳時間:	2026-04-23 11:31:01 (UTC+8)
出版者:	Springer New York;New York: Springer New York
摘要:	摘要： This work reports on the diameter-sensitive biocompatibility of anodic TiO 2 nanotubes with different nanotube diameters grown by a self-ordering process and subsequently treated with supercritical CO 2 (ScCO 2 ) fluid. We find that highly hydrophilic as-grown TiO 2 nanotubes become hydrophobic after the ScCO 2 treatment but can effectively recover their surface wettability under UV light irradiation as a result of photo-oxidation of C-H functional groups formed on the nanotube surface. It is demonstrated that human fibroblast cells show more obvious diameter-specific behavior on the ScCO 2 -treated TiO 2 nanotubes than on the as-grown ones in the range of diameters of 15 to 100 nm. This result can be attributed to the removal of disordered Ti(OH) 4 precipitates from the nanotube surface by the ScCO 2 fluid, thus resulting in purer nanotube topography and stronger diameter dependence of cell activity. Furthermore, for the smallest diameter of 15 nm, ScCO 2 -treated TiO 2 nanotubes reveal higher biocompatibility than the as-grown sample. 其他題名： Nanoscale Res Lett 出版者： New York: Springer New York 出版日期： 2013-04-02 出處： Nanoscale research letters, 2013-04, Vol.8 (1), p.150-150, Article 150 資源來源： Publicly Available Content Database 版權： Lan et al.; licensee Springer. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 版權： The Author(s) 2013 版權： Copyright ©2013 Lan et al.; licensee Springer. 2013 Lan et al.; licensee Springer. 識別號： ISSN: 1556-276X 識別號： ISSN: 1931-7573 識別號： EISSN: 1556-276X 識別號： DOI: 10.1186/1556-276X-8-150 識別號： PMID: 23547743
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