Fabrication and characterizations of thin film metallic glasses: Antibacterial property and durability study for medical application

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Title:	Fabrication and characterizations of thin film metallic glasses: Antibacterial property and durability study for medical application
Authors:	鄭憲清;Chu, Jinn P.;Liu, Tz-Yah;Li, Chia-Lin;Wang, Chen-Hao;Jang, Jason S.C.;Chen, Ming-Jen;Chang, Shih-Hsin;Huang, Wen-Chien
Contributors:	工學院材料科學與工程研究所
Keywords:	Abrasion resistance;Amorphous materials;Antibacterial property;Bacteria;Copper;Durability;Escherichia coli;Metallic glass;Metallic glasses;Staphylococcus aureus;Thin films;Zirconium
Date:	2014-06-30
Issue Date:	2026-04-23 11:34:38 (UTC+8)
Publisher:	Elsevier;Elsevier B.V
Abstract:	摘要： Metallic glasses with the disordered atomic structure have unique properties of high strength, high toughness, good corrosion and abrasion resistances. These materials are thus potentially useful for medical application. In this work, we evaluate the antibacterial property and durability of materials sputter-coated with Zr-based (Zr53Cu33Al9Ta5) and Cu-based (Cu48Zr42Ti4Al6) thin film metallic glasses (TFMGs). Good adhesive coating of Zr-based TFMG on the dermatome gives rise to blade sharpness improvement of ~27%, substantial surface roughness reduction of ~66% and smoother incised wound on the pig skin. As compared to 48.8° on the bare Si wafer, the water contact angles of 119.5° and 106.6° for Zr- and Cu-based TFMGs, respectively, reveal the hydrophobic characteristic of the coated surfaces. The bacterial adhesion of Escherichia coli and Staphylococcus aureus to both Zr- and Cu-based TFMGs is hindered to different extents. •Thin film metallic glass (TFMG) coatings are evaluated for medical application.•Good adhesive TFMG on the dermatome yields blade sharpness improvement of ~27%.•A reduction of ~66% in surface roughness is observed after coating with TFMG.•Water contact angle measurement reveals the hydrophobic characteristic for TFMGs.•Bacterial adhesion of E. coli and S. aureus to TFMGs is hindered. 出版者： Elsevier B.V 出版日期： 2014-06-30 出處： Thin solid films, 2014-06, Vol.561, p.102-107 版權： 2013 Elsevier B.V. 識別號： ISSN: 0040-6090 識別號： EISSN: 1879-2731 識別號： DOI: 10.1016/j.tsf.2013.08.111
Appears in Collections:	[Institute of Materials Science and Engineering] journal & Dissertation

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