Risk of dementia after anaesthesia and surgery

Please use this identifier to cite or link to this item: https://ir.lib.ncu.edu.tw/handle/987654321/105885

Title:	Risk of dementia after anaesthesia and surgery
Authors:	曾議寬;Chen, Pin-Liang;Yang, Chih-Wen;Tseng, Yi-Kuan;Sun, Wei-Zen;Wang, Jane-Ling;Wang, Shuu-Jiun;Oyang, Yen-Jen;Fuh, Jong-Ling
Contributors:	理學院統計研究所
Keywords:	Age;Aged;Alzheimer's disease;Anaesthesia;Anesthesia;Anesthesia - adverse effects;Anesthesia - statistics & numerical data;Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy;Anesthesiology;Biological and medical sciences;Cancer therapies;Case-Control Studies;Cognitive ability;Dementia;Dementia - chemically induced;Dementia - epidemiology;Dementia disorders;Drug toxicity and drugs side effects treatment;Female;First time;Gender;General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation;Hazards;Humans;Intravenous administration;Male;Medical diagnosis;Medical sciences;Memory;Middle Aged;Neurotoxicity;Older people;Patients;Pharmacology. Drug treatments;Population studies;Psychiatry;Risk;Risk Factors;Stroke;Surgery;Surgical Procedures, Operative - adverse effects;Surgical Procedures, Operative - statistics & numerical data;Taiwan - epidemiology;Toxicity: nervous system and muscle
Date:	2014-01-01
Issue Date:	2026-04-23 12:59:07 (UTC+8)
Publisher:	Royal College of Psychiatrists;Cambridge, UK: Cambridge University Press
Abstract:	摘要： The potential relationship between anaesthesia, surgery and onset of dementia remains elusive. To determine whether the risk of dementia increases after surgery with anaesthesia, and to evaluate possible associations among age, mode of anaesthesia, type of surgery and risk of dementia. The study cohort comprised patients aged 50 years and older who were anaesthetised for the first time since 1995 between 1 January 2004 and 31 December 2007, and a control group of randomly selected patients matched for age and gender. Patients were followed until 31 December 2010 to identify the emergence of dementia. Relative to the control group, patients who underwent anaesthesia and surgery exhibited an increased risk of dementia (hazard ratio = 1.99) and a reduced mean interval to dementia diagnosis. The risk of dementia increased in patients who received intravenous or intramuscular anaesthesia, regional anaesthesia and general anaesthesia. The results of our nationwide, population-based study suggest that patients who undergo anaesthesia and surgery may be at increased risk of dementia. 其他題名： Br J Psychiatry 出版者： Cambridge, UK: Cambridge University Press 出版日期： 2014-03-01 出處： British journal of psychiatry, 2014-03, Vol.204 (3), p.188-193 版權： Copyright © Royal College of Psychiatrists, 2014 版權： 2015 INIST-CNRS 版權： Royal College of Psychiatrists 2014 識別號： ISSN: 0007-1250 識別號： ISSN: 1472-1465 識別號： EISSN: 1472-1465 識別號： DOI: 10.1192/bjp.bp.112.119610 識別號： PMID: 23887997 識別號： CODEN: BJPYAJ
Appears in Collections:	[Graduate Institute of Statistics] journal & Dissertation

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