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    請使用永久網址來引用或連結此文件: https://ir.lib.ncu.edu.tw/handle/987654321/106293


    題名: Analysis and construction of genetic network for mice brain microarray datasets
    作者: 洪炯宗;Chen, Jui-Ming;Liu, Yu-An;Jung, Yu-Ling;Chan, Yung-Kuan;Horng, Jorng-Tzong;Syu, Jen-Hui;Tsai, Meng-Hsiun
    貢獻者: 資訊電機學院資訊工程學系
    關鍵詞: Brain;Calcium channel;EI;Gene network;Learning;Memory learning;Pearson coefficient of correlation;SCI
    日期: 2013-09-17
    上傳時間: 2026-04-23 13:16:46 (UTC+8)
    出版者: Springer International Publishing AG;台灣: 中華民國生物醫學工程學會
    摘要: 摘要: This paper intends to find out target genes about memory and learning via microarray analysis. Microarrays are often used to store and manage large amounts of data; however, there is no consensus as to how to best analyze microarray data. This paper uses computational algorithms to analyze gene samples from mice with various calcium channel phenotypes. Min-max normalization was used first to normalize the data. Then, analysis of variance was applied to detect genetic differences among the genes. Finally, Pearson correlation coefficients were calculated to identify the regulatory network of the genes. This analysis model can be applied to efficiently analyze complicated gene expression data. It can also be used to examine the biological functions and regulations of target genes.
    出版者: 台灣: 中華民國生物醫學工程學會
    出版日期: 2013-01-01
    出處: Journal of Medical and Biological Engineering, 2013-01, Vol.33 (4), p.400-405
    資源來源: 華藝CEPS中文電子期刊服務
    識別號: ISSN: 1609-0985
    識別號: DOI: 10.5405/jmbe.1310
    顯示於類別:[資訊工程學系] 期刊論文

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