Exploring the impact of intravenous thrombolysis on length of stay for acute ischemic stroke: A retrospective cohort study

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Title:	Exploring the impact of intravenous thrombolysis on length of stay for acute ischemic stroke: A retrospective cohort study
Authors:	胡雅涵;Hung, Ling-Chien;Hu, Ya-Han;Sung, Sheng-Feng
Contributors:	管理學院資訊管理學系
Keywords:	Aged;Aged, 80 and over;Cardiac arrhythmia;Cardiovascular disease;Care and treatment;Complications and side effects;Costs;Data mining;Decision trees;Diabetes;Female;Health Administration;Health care expenditures;Health care policy;Health Informatics;Heart failure;Hospitalization;Hospitals;Humans;Ischemia;Length of Stay;Logistic Models;Male;Medical research;Medicine;Medicine & Public Health;Medicine, Experimental;Middle Aged;Mortality;Nursing Research;Odds Ratio;Older people;Patient Discharge;Patient outcomes;Patients;Public Health;Registries;Regression analysis;Research Article;Retrospective Studies;Stroke;Stroke (Disease);Stroke - therapy;Thrombolytic drugs;Thrombolytic Therapy;Tomography;Treatment Outcome;United States;Variables
Date:	2015-09-23
Issue Date:	2026-04-23 13:36:21 (UTC+8)
Publisher:	London: Springer Science and Business Media LLC
Abstract:	摘要： Background Understanding the factors that influence the hospital length of stay (LOS) for patients with stroke will help in discharge planning and stroke unit management. We explored how intravenous thrombolysis (IVT) affects LOS in an acute-care hospital setting. Methods We analyzed adult patients with ischemic stroke who presented within 48 h of onset from a hospital-based stroke registry. The relationship between IVT and prolonged LOS (LOS ≥ 7 days) was studied by both multivariate logistic regression and the classification and regression tree (CART) analyses. Results Among the study population of 3054 patients, 1110 presented within 4.5 h. The median LOS (interquartile range) was 7 (4 to 11) days, and 1619 patients had prolonged LOS. Multivariate logistic regression revealed that IVT (odds ratio, 0.53; 95 % confidence interval 0.38–0.74) was an independent factor that reduced the risk of prolonged LOS, whereas age, National Institutes of Health Stroke Scale (NIHSS) score, diabetes mellitus, and leukocytosis at admission predicted prolonged LOS. CART analysis identified 4 variables (NIHSS score, IVT, leukocytosis at admission, and age) as important factors to partition the patients into six subgroups. The patient subgroup that had an NIHSS score of 5 to 7 and received IVT had the lowest probability (19 %) of prolonged LOS. Conclusions IVT reduced the risk of prolonged LOS in patients with acute ischemic stroke. Measures to increase the rate of IVT are encouraged. 其他題名： BMC Health Serv Res 出版者： London: Springer Science and Business Media LLC 出版日期： 2015-09-23 出處： BMC Health Services Research, 2015-09, Vol.15 (1), p.404, Article 404 資源來源： Healthcare Administration Database (Proquest) 版權： Hung et al. 2015 版權： COPYRIGHT 2015 BioMed Central Ltd. 版權： Copyright BioMed Central 2015 識別號： ISSN: 1472-6963 識別號： EISSN: 1472-6963 識別號： DOI: 10.1186/s12913-015-1080-0 識別號： PMID: 26399930
Appears in Collections:	[Department of Information Management] journal & Dissertation

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