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    题名: Inhibitory repetitive transcranial magnetic stimulation of the contralesional premotor and primary motor cortices facilitate poststroke motor recovery
    作者: 葉士青;Wang, Chien-Chih;Wang, Chih-Pin;Tsai, Po-Yi;Hsieh, Chin-Yi;Chan, Rai-Chi;Yeh, Shih-Ching
    贡献者: 資訊電機學院資訊工程學系
    关键词: Aged;Chronic Disease;Double-Blind Method;Female;Functional Laterality;Functional Laterality - physiology;Humans;Male;Middle Aged;Motor Cortex;Motor Cortex - physiopathology;Motor Skills;Motor Skills - physiology;Neural Inhibition;Neural Inhibition - physiology;Recovery of Function;Recovery of Function - physiology;Severity of Illness Index;Stroke;Stroke - physiopathology;Stroke - therapy;Transcranial Magnetic Stimulation;Transcranial Magnetic Stimulation - methods;Treatment Outcome
    日期: 2014-01-01
    上传时间: 2026-04-23 13:48:23 (UTC+8)
    出版者: London, England: SAGE Publications
    摘要: 摘要: Purpose: The premotor cortex plays a major role in motor planning and control, exhibiting hierarchical importance comparable to that of the primary motor cortex (M1). In this study, we compared the effects of cPMd modulation, which was achieved using inhibitory repetitive transcranial magnetic stimulation (rTMS), with those of contralesional M1 (cM1) modulation, to elucidate the roles of both regions on longitudinal motor recovery following a stroke. Methods: Forty-four patients who had sustained hemiplegia for 3 to 12 months were randomly allocated to a cPMd group, cM1 group, or sham group and received 10 sessions of 1-Hz rTMS. The Medical Research Council (MRC) Scale, Fugl-Meyer Assessment (FMA), Wolf Motor Function Test (WMFT), and a cortical excitability test were administered pre- and post- rTMS intervention. Results: cPMd modulation yielded significant improvements in MRC, FMA, and WMFT scores compared with sham stimulation and a significant effect on cortical excitability suppression equivalent to that of cM1 modulation, but engendered effects on motor improvement inferior to those of cM1 modulation. Conclusions: In patients with chronic stroke, the cPMd can fulfill a role similar to that of the cM1 in interhemispheric imbalance, which can be ameliorated by applying inhibitory rTMS to achieve substantial motor restoration.
    其他題名: Restor Neurol Neurosci
    出版者: London, England: SAGE Publications
    出版日期: 2014
    出處: Restorative neurology and neuroscience, 2014, Vol.32 (6), p.825-835
    資源來源: EBSCOhost Academic Search Premier
    版權: IOS Press. All rights reserved
    識別號: ISSN: 0922-6028
    識別號: ISSN: 1878-3627
    識別號: EISSN: 1878-3627
    識別號: DOI: 10.3233/RNN-140410
    識別號: PMID: 25201815
    显示于类别:[資訊工程學系] 期刊論文

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