摘要: We demonstrate porous silicon biological probes as a stable and non-toxic alternative to organic dyes or cadmium-containing quantum dots for imaging and sensing applications. The fluorescent silicon quantum dots which are embedded on the porous silicon surface are passivated with carboxyl-terminated ligands through stable Si-C covalent bonds. The porous silicon bio-probes have shown photoluminescence quantum yield around 50% under near-UV excitation, with high photochemical and thermal stability. The bio-probes can be efficiently conjugated with antibodies, which is confirmed by a standard enzyme-linked immunosorbent assay (ELISA) method. 其他題名: Opt Express 出版者: United States 出版日期: 2014-12-01 出處: Optics express, 2014-12, Vol.22 (24), p.29996 資源來源: Optica Publishing Group Journals 識別號: ISSN: 1094-4087 識別號: EISSN: 1094-4087 識別號: DOI: 10.1364/OE.22.029996 識別號: PMID: 25606929