Syntheses and fungicidal activities of thiazole-5-carboxanilides bearing thioether group

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题名:	Syntheses and fungicidal activities of thiazole-5-carboxanilides bearing thioether group
作者:	劉愛萍;Xue, Hansong;Liu, Aiping;Liu, Weidong;Li, Jianming;Ren, Yeguo;Huang, Lu;He, Lian;Ou, Xiaoming;Ye, Jiao;Huang, Mingzhi
贡献者:	總教學中心語言中心
关键词:	Analytical Chemistry;Aniline;Chemical synthesis;Chemistry;Chemistry and Materials Science;Chemistry/Food Science;Fungicides;Inorganic Chemistry;Organic Chemistry;Pathogens;Physical Chemistry;Sulfur
日期:	2016-10-01
上传时间:	2026-04-23 14:27:46 (UTC+8)
出版者:	Springer International Publishing AG;Changchun: Jilin University and The Editorial Department of Chemical Research in Chinese Universities
摘要:	摘要： In an attempt to find leading thiazole carboxanilides exhibiting fungicidal activities, we designed and synthesized a new series of 2-sulfursubstituted thiazole carboxanilides via the reaction between 2-sulfur substituted thiazole carboxylic acid chlorides and substituted aniline. The fungicidal activities of the title compounds against Rhizoctonia solani were screened and the results were remarkable. The most potent compound 8 i, N -[2,6-dichloro-4-(trifluoromethyl)phenyl]-2-methylthio-4-(trifluoromethyl)thiazole-5-carboxamide, was identified. The fungicidal EC 50 of compound 8 i against Rhizoctonia solani was 1.28 mg/L, being comparable to that of Thifluzamide. The results indicate that compound 8 i can be considered as a lead compound for further research. 其他題名： Chem. Res. Chin. Univ 出版者： Changchun: Jilin University and The Editorial Department of Chemical Research in Chinese Universities 出版日期： 2016-10-01 出處： Chemical research in Chinese universities, 2016-10, Vol.32 (5), p.781-785 版權： Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH 2016 版權： Copyright Springer Science & Business Media 2016 識別號： ISSN: 1005-9040 識別號： EISSN: 2210-3171 識別號： DOI: 10.1007/s40242-016-6153-z
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