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| 題名: | Reduced enhancement of high-frequency component in the cross spectrum of ECG and nostril airflow signals in patients with chronic obstructive pulmonary disease |
| 作者: | 蔡章仁;Lu, Wan‐An;Kuo, Jane;Wang, Yan‐Min;Lien, Te‐Cheng;Liu, Yen‐Bin;Tsai, Jang‐Zern;Kuo, Cheng‐Deng |
| 貢獻者: | 資訊電機學院電機工程學系 |
| 關鍵詞: | Aged;Aged, 80 and over;Airway Resistance;Allergic diseases;Body mass index;Cardiology;Case-Control Studies;Chronic obstructive pulmonary disease;Control of Breathing;cross‐spectral analysis;Disease resistance;Drug dosages;EKG;electrocardiogram;Electrocardiography;Female;Forced Expiratory Volume;Fourier Analysis;Heart;Heart Rate;heart rate variability;Humans;Lung diseases;Male;Mortality;Nose - physiopathology;Obstructive lung disease;Original Research;Patients;Physiology;Predictive Value of Tests;Prospective Studies;Pulmonary Disease, Chronic Obstructive - diagnosis;Pulmonary Disease, Chronic Obstructive - physiopathology;Respiration;Respiratory Conditions Disorder and Diseases;Respiratory function;Respiratory Rate;Respiratory tract diseases;Signal Processing, Computer-Assisted;Task forces;Time Factors;Time series;Vital Capacity |
| 日期: | 2016-04-01 |
| 上傳時間: | 2026-04-23 14:36:14 (UTC+8) |
| 出版者: | John Wiley and Sons Inc.;United States: John Wiley & Sons, Inc |
| 摘要: | 摘要： Chronic obstructive pulmonary disease (COPD) is a chronic airway disease with increased airway resistance. This study investigated the common characteristics of electrocardiographic (ECG) and nostril airflow signals in COPD patients using cross‐spectral analysis. Heart rate variability (HRV) measures and cross‐spectral (cs) measures of ECG and nostril airflow were compared in COPD patients and normal subjects, and correlated with their clinical characteristics. We found that cross‐spectral analysis can lead to a significant increase in normalized high‐frequency power (nHFPcs) and a significant decrease in normalized very low‐frequency power (nVLFPcs), normalized low‐frequency power (nLFPcs), and low‐/high‐frequency power ratio (LHRcs) in both normal subjects and COPD patients, as compared with their corresponding HRV measures. Further analysis showed that the percentage increase in nHFP (%nHFP) and the percentage decrease in LHR (%LHR) due to cross‐spectral analysis in COPD patients were significantly smaller than those of normal subjects. All cross‐spectral measures of ECG and nostril airflow in COPD patients did not significantly correlate with their pulmonary function characteristics. However, the nHFPcs correlated significantly and negatively with body mass index (BMI) in both normal subjects and COPD patients, and the %nHFP correlated significantly and negatively with BMI in COPD patients. We conclude that cross‐spectral analysis of ECG and nostril airflow signals could lead to reduced enhancement in the high‐frequency component in the cross spectrum of COPD patients. The magnitude of reduced enhancement in the high‐frequency component in the cross‐spectrum was related to the BMI of the patients. Cross‐spectral analysis of ECG and nostril airflow might be used to assess the cardiovascular‐related functions of COPD patients. This was the first simultaneous application of cross‐spectral analysis of ECG and nostril airflow signals, and heart rate variability analysis to patients with chronic obstructive pulmonary disease. It was found that cross‐spectral analysis of ECG and nostril airflow signals could lead to a reduced enhancement in the high‐frequency component in the cross‐spectrum of Chronic obstructive pulmonary disease (COPD) patients. The magnitude of reduced enhancement in the high‐frequency component was related to the body mass index of the patients.
其他題名： Physiol Rep
出版者： United States: John Wiley & Sons, Inc
出版日期： 2016-04
出處： Physiological reports, 2016-04, Vol.4 (7), p.e12763-n/a
資源來源： ProQuest
版權： 2016 The Authors. published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.
版權： 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.
版權： 2016. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
識別號： ISSN: 2051-817X
識別號： EISSN: 2051-817X
識別號： DOI: 10.14814/phy2.12763
識別號： PMID: 27053296 |
| 顯示於類別: | [電機工程學系] 期刊論文
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