Ten Years of Theta Burst Stimulation in Humans: Established Knowledge, Unknowns and Prospects

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題名:	Ten Years of Theta Burst Stimulation in Humans: Established Knowledge, Unknowns and Prospects
作者:	黃英儒;Suppa, A.;Huang, Y.-Z.;Funke, K.;Ridding, M.C.;Cheeran, B.;Di Lazzaro, V.;Ziemann, U.;Rothwell, J.C.
貢獻者:	生醫理工學院認知神經科學研究所
關鍵詞:	Adult;Animal model;Animals;Evoked Potentials, Motor - physiology;Female;Health Knowledge, Attitudes, Practice;Humans;Long-Term Potentiation - physiology;Motor Cortex - physiology;Motor Cortex - physiopathology;Movement Disorders - physiopathology;Movement Disorders - therapy;Neurology;Neuronal Plasticity - physiology;Plasticity;Primary motor cortex;Theta burst stimulation;Theta Rhythm - physiology;Transcranial Magnetic Stimulation - methods
日期:	2016-05-01
上傳時間:	2026-04-23 14:39:15 (UTC+8)
出版者:	Elsevier Inc.;United States: Elsevier Inc
摘要:	摘要： •This review focuses on TBS studies in healthy subjects and in patients with movement disorders.•This review also focuses on the experimental evidence coming from TBS studies in animals.•This review discuss the status of TBS as a possible new non-invasive therapy aimed at improving symptoms in various types of neurological disorders Over the last ten years, an increasing number of authors have used the theta burst stimulation (TBS) protocol to investigate long-term potentiation (LTP) and long-term depression (LTD)-like plasticity non-invasively in the primary motor cortex (M1) in healthy humans and in patients with various types of movement disorders. We here provide a comprehensive review of the LTP/LTD-like plasticity induced by TBS in the human M1. A workgroup of researchers expert in this research field review and discuss critically ten years of experimental evidence from TBS studies in humans and in animal models. The review also includes the discussion of studies assessing responses to TBS in patients with movement disorders. We discuss experimental studies applying TBS over the M1 or in other cortical regions functionally connected to M1 in healthy subjects and in patients with various types of movement disorders. We also review experimental evidence coming from TBS studies in animals. Finally, we clarify the status of TBS as a possible new non-invasive therapy aimed at improving symptoms in various neurological disorders. 其他題名： Brain Stimul 出版者： United States: Elsevier Inc 出版日期： 2016-05-01 出處： Brain Stimulation, 2016-05, Vol.9 (3), p.323-335 資源來源： Alma/SFX Local Collection 版權： 2016 Elsevier Inc. 版權： Elsevier Inc. 版權： Copyright © 2016 Elsevier Inc. All rights reserved. 識別號： ISSN: 1935-861X 識別號： ISSN: 1876-4754 識別號： EISSN: 1876-4754 識別號： DOI: 10.1016/j.brs.2016.01.006 識別號： PMID: 26947241
顯示於類別:	[認知與神經科學研究所 ] 期刊論文

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