Biomechanical effects of disc degeneration and hybrid fixation on the transition and adjacent lumbar segments: Trade-off between junctional problem, motion preservation, and load protection

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题名:	Biomechanical effects of disc degeneration and hybrid fixation on the transition and adjacent lumbar segments: Trade-off between junctional problem, motion preservation, and load protection
作者:	黃俊仁;Chuang, Wen-Hsien;Lin, Shang-Chih;Chen, Shih-Hao;Wang, Chih-Wei;Tsai, Wen-Chi;Chen, Yeung-Jen;Hwang, Jiun-Ren
贡献者:	工學院機械工程學系
关键词:	Adult;Biomechanical Phenomena - physiology;Bone Screws;Humans;Internal Fixators;Intervertebral Disc Degeneration - physiopathology;Intervertebral Disc Degeneration - surgery;Lumbar Vertebrae - physiopathology;Lumbar Vertebrae - surgery;Male;Range of Motion, Articular - physiology;Spinal Fusion - methods;Stress, Mechanical;Weight-Bearing - physiology
日期:	2012-11-15
上传时间:	2026-04-23 14:47:00 (UTC+8)
出版者:	United States
摘要:	摘要： The biomechanical effects of disc degeneration and hybrid fixation on the transition and adjacent segments were evaluated using a numerical approach. This study aimed to evaluate the rigidity-rising effects of the dehydrated disc and bridged fixator on the kinematic and mechanical redistribution of the transition and adjacent segments. After static fixation, a dynamic fixator can be used to preserve motion and share loads for the transition segments. However, the hybrid use of both static and dynamic fixators and its effects on the biomechanical behavior of the transition and adjacent segments were not investigated extensively. A nonlinear and osseoligamentous lumbar model from L1 vertebra to S1 vertebrae was developed. Ligament interconnection, muscular contraction, and weight compression were all used to simulate lumbar flexion. The static fixator was instrumented at the degenerative L4-L5 segment and the dynamic fixators (Dynesys system) with different stiffness were subsequently applied to the degenerative or healthy L3-L4 segment. A healthy lumbar model was used as a reference point for further comparison and evaluation. The predicted results were validated with the cadaveric and numerical values of the literature studies. Among the 21 models, the junctional problem at the adjacent (L2/L3 and L5/S1) discs as well as the motion preservation and stress distribution at the transition (L3/L4) disc were compared. Static fixation and the degenerative disc deteriorated the junctional problem at adjacent segments. On average, the hybrid fixation of the original Dynesys cord constrained the range of motion (ROM) by 65%. Furthermore, it shared 43% of the stress on the transition disc. However, this resulted in the adjacent discs increasing about 50% ROM and 40% stress. The term "trade-off stiffness" was used to express the concept that the decreased stiffness of the original cord could balance the junctional problem, motion preservation, and load protection of the transition and adjacent segments. The trade-off stiffness of the degenerative transition disc was higher than that of the healthy disc. Compared with the original design, the increased ROM and stress of the adjacent segments can be reduced by about 43% using the trade-off stiffness. The use of the hybrid fixator should involve a certain trade-off between the protection of the transition segment and the deterioration of the adjacent segments. This trade-off stiffness, which largely depends on both fixator design and disc degeneration, provides the improved rigidity and flexibility of the transition and adjacent segments. 其他題名： Spine (Phila Pa 1976) 出版者： United States 出版日期： 2012-11-15 出處： Spine (Philadelphia, Pa. 1976), 2012-11, Vol.37 (24), p.E1488-E1497 識別號： ISSN: 0362-2436 識別號： ISSN: 1528-1159 識別號： EISSN: 1528-1159 識別號： DOI: 10.1097/BRS.0b013e31826cdd93 識別號： PMID: 22872225
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