Royal Society of Chemistry;Cambridge: Royal Society of Chemistry
摘要:
摘要： Matrix-assisted laser desorption/ionization mass spectrometry is an established soft ionization method that is widely applied to analyze biomolecules. The UV-absorbing organic matrix is essential for biomolecule ionization; however, it also creates matrix background interference, which results in problematic analyses of biomolecules of less than 700 Da. Therefore, this study investigates hydrophilic, hydrophobic cationic, anionic and immobilized metal ion surface chemical modifications to advance nanostructured silicon mass spectrometry performance (nSi-MS). This investigation provides information required for a possible novel mass spectroscopy that combines surface-enhanced and nanostructured silicon surface-assisted laser desorption/ionization mass spectrometry for the selective detection of specific compounds of a mixture. This study investigates various surface chemical modifications to nanostructured silicon mass spectrometry (nSi-MS) for a possible novel mass spectroscopy that combines surface-enhanced and nanostructured silicon SALDI Mass spectrometry. 其他題名： Analyst 出版者： Cambridge: Royal Society of Chemistry 出版日期： 2012-06-07 出處： Analyst (London), 2012-06, Vol.137 (11), p.2643-265 資源來源： Royal Society of Chemistry 版權： 2015 INIST-CNRS 識別號： ISSN: 0003-2654 識別號： ISSN: 1364-5528 識別號： EISSN: 1364-5528 識別號： DOI: 10.1039/c2an35189g 識別號： PMID: 22531330 識別號： CODEN: ANALAO
