摘要： Progressive narrowing of the upper airway increases airflow resistance and can produce snoring sounds and apnea/hypopnea events associated with sleep-disordered breathing due to airway collapse. Recent studies have shown that acoustic properties during snoring can be altered with anatomic changes at the site of obstruction. To evaluate the instantaneous association between acoustic features of snoring and the anatomic sites of obstruction, a novel method was developed and applied in nine patients to extract the snoring sounds during sleep while performing dynamic magnetic resonance imaging (MRI). The degree of airway narrowing during the snoring events was then quantified by the collapse index (ratio of airway diameter preceding and during the events) and correlated with the synchronized acoustic features. A total of 201 snoring events (102 pure retropalatal and 99 combined retropalatal and retroglossal events) were recorded, and the collapse index as well as the soft tissue vibration time were significantly different between pure retropalatal (collapse index, 24 ± 11%; vibration time, 0.2 ± 0.3 s) and combined (retropalatal and retroglossal) snores (collapse index, 13 ± 7% [P ≤ 0.0001]; vibration time, 1.2 ± 0.7 s [P ≤ 0.0001]). The synchronized dynamic MRI and acoustic recordings successfully characterized the sites of obstruction and established the dynamic relationship between the anatomic site of obstruction and snoring acoustics. 其他題名： PM 其他題名： Physiol. Meas 出版者： England: IOP Publishing 出版日期： 2014-12-01 出處： Physiological measurement, 2014-12, Vol.35 (12), p.2501-2512 資源來源： IoP Science journals 版權： 2014 Institute of Physics and Engineering in Medicine 識別號： ISSN: 0967-3334 識別號： ISSN: 1361-6579 識別號： EISSN: 1361-6579 識別號： DOI: 10.1088/0967-3334/35/12/2501 識別號： PMID: 25402604 識別號： CODEN: PMEAE3
