中大機構典藏-NCU Institutional Repository-提供博碩士論文、考古題、期刊論文、研究計畫等下載:Item 987654321/26619
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 70585/70585 (100%)
造访人次 : 23076632      在线人数 : 363
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.lib.ncu.edu.tw/handle/987654321/26619


    题名: Studies on epoxy compound fixation
    作者: Sung,HW;Cheng,WH;Chiu,IS;Hsu,HL;Liu,SA
    贡献者: 化學工程與材料工程學系
    关键词: HEART-VALVE BIOPROSTHESIS;GLUTARALDEHYDE;COLLAGEN;CALCIFICATION;BIOMATERIALS;PREVENTION;DERMATITIS;CONDUIT;GRAFTS
    日期: 1996
    上传时间: 2010-06-29 17:32:31 (UTC+8)
    出版者: 中央大學
    摘要: Bioprostheses derived from collagenous tissues have to be fixed and subsequently sterilized before they can be implanted in humans, Clinically, the most commonly used fixative is glutaraldehyde, However, the tendency for glutaraldehyde to markedly alter tissue stiffness and promote tissue calcification are well-recognized drawbacks of this fixative. To address the deficiencies with the glutaraldehyde-fixed tissue, a new fixative, epoxy compound, was used to fix biological prostheses, The study was undertaken to investigate the fixation rates and crosslinking densities of biological tissues fixed with various epoxy compounds. These epoxy compounds are different in their chemical structures, Glutaraldehyde was used as a control, The fixation rates and crosslinking densities of the fixed tissues were determined by measuring their fixation indices and denaturation temperatures, respectively. Generally, the epoxy-fixed tissues were more pliable than the glutaraldehyde-fixed one. Furthermore, the tissues fixed with monofunctional epoxy compound were more pliable than those fixed with multifunctional epoxy compounds. With increasing pH or temperature, the fixation rate of epoxy compound increased, However, the number of epoxide functional groups did not seem to affect the fixation rate of the epoxy compound. The fixation rate of glutaraldehyde was faster than that of epoxy compounds, Additionally, the crosslinking density of the glutaraldehyde-fixed tissue was greater than that of the epoxy-fixed counterparts, Moreover, it was noted that the denaturation temperatures of the tissues fixed with glutaraldehyde or multifunctional epoxy compounds were significantly higher than the fresh ones (p <0.05), while that fixed with monofunctional epoxy compound stayed roughly the same throughout the entire fixation process (p >0.05). The results obtained in this study may be used to optimize the fixation process for developing bioprostheses fixed with epoxy compounds. (C) 1996 John Wiley & Sons, Inc.
    關聯: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
    显示于类别:[化學工程與材料工程研究所] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML329检视/开启


    在NCUIR中所有的数据项都受到原著作权保护.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈  - 隱私權政策聲明