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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/33632


    Title: Unique actinomycin D binding to self-complementary d(CXYGGCCY ' X ' G) sequences: duplex disruption and binding to a nominally base-paired hairpin
    Authors: Chen,FM;Sha,F;Chin,KH;Chou,SH
    Contributors: 生命科學研究所
    Keywords: SINGLE-STRANDED-DNA;TETRANUCLEOTIDE SEQUENCES;GPC SITES;MODEL;DRUG;SPECIFICITIES;ASSOCIATION;COMPLEX;XGCY
    Date: 2003
    Issue Date: 2010-07-07 11:40:14 (UTC+8)
    Publisher: 中央大學
    Abstract: Actinomycin D (ACTD) has been shown to bind weakly to the sequence -GGCC-, despite the presence of a GpC site. It was subsequently found, however, that d(CATGGCCATG) binds relatively well to ACTD but exhibits unusually slow association kinetics, contrary
    Relation: NUCLEIC ACIDS RESEARCH
    Appears in Collections:[生命科學研究所 ] 期刊論文

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