| 摘要: | 十二烷基硫酸鈉(SDS)為高水溶性化合物，並且為常用的表面活性劑之一。在文獻報導中，十二烷基硫酸鈉具有4種水合物，分別為1/8水、半水、一水以及無水。但是製成端方面較少文獻提到如何控制SDS為何種水合物。因此本篇論文主要目的為採取工業上常用批式結晶，並結合蒸發結晶、反溶劑結晶以及冷卻結晶製造出特定SDS·1/8水合物。買來的0.5克SDS以定量的方式浸泡在由水及丙酮組成的1比17之體積比的共溶劑以製造SDS·1/8水合物。在合併結晶製程中，255毫升的丙酮作為反溶劑加入結晶槽。此合併結晶製程的產率為83％，所生產出來的SDS經由傅里葉變換紅外光譜（FTIR）、熱重分析（TGA）、差示掃描量熱法(DSC)和粉末X射線衍射（PXRD）鑑定推測為SDS·1/8水合物。最後將生產出來的SDS·1/8水合物放置25、52、75%不同濕度之環境放置5天測試穩定度。經由穩定度測試下，生產出來的SDS·1/8水合物是很穩定的水合物型式;Sodium dodecyl sulfate (SDS) was highly water soluble compound and was one of the commonly used surfactants. In previous studies, hydrate forms of SDS, 1/8 hydrate, hemihydrate, monohydrate, and anhydrous had been reported. However, there are few studies mentioned how to control the hydrate forms for SDS in the manufacturing process. Therefore, the aim of this thesis was to produce exact SDS·1/8 hydrate, through the combined process of evaporative, anti-solvent, cooling crystallization, and co-solvent system in batch system. First, purchased SDS crystals were immersed into the 1:17 volume ratio of co-solvent composed of water to acetone (v/v)) for preparation of SDS·1/8 hydrate. In combined process, 255mL of acetone was chosen as anit-solvent to introduce into crystallizer. Finally, produced SDS·1/8 hydrate was tested stability by exploring at 25, 52 and 75% relative humidity. The yield for the combined crystallization process was about 83%. The produced SDS was speculated to be SDS·1/8 hydrate, by characterization of Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and powder X-ray diffraction (PXRD). The result of stability test demonstrated that the produced SDS·1/8 hydrate was a stable form. |
