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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/94067


    Title: 發展心臟內虛擬電造影技術實踐數位孿生心臟於心律失常性心肌病變及冠狀動脈疾病之早期偵測及定位;Developing Personalized Digital Twins of Heart by Computational Cardiac Electrophysiological Model for Early Detection and the Culprit-Lesion Location of Arrhythmogenic Cardiomyopathy and Coronary Artery Disease
    Authors: 羅孟宗;林亮宇;林彥璋
    Contributors: 國立中央大學生醫科學與工程學系
    Keywords: 心室心搏過速;心室心律不整;心肌基質;虛擬電生理;心電圖;體表電位映射;稀疏表示式;自編碼機;心肌細胞模型;心肌缺血;Ventricular Tachycardia;Ventricular Fibrillation;Myocardial Substrate;Virtual Electrophysiology;Electrocardiograph Imaging;Body Surface Potential Mapping;Sparse Representation;Auto-Encoder;myocardial ischemia
    Date: 2024-09-27
    Issue Date: 2024-09-30 15:50:51 (UTC+8)
    Publisher: 國家科學及技術委員會(本會)
    Abstract: 本計畫基於物理學與生理學的全心臟模擬技術,計算不同病徵下的心臟外膜電位分布與其對應的體表電位分布,並集結成數據集,利用稀疏表示式分類模型將實際量測的體表心電圖對應至模擬數據集的最佳解,而後產生虛擬心臟三維電氣分布。本計畫建構的非侵入式體表心電圖造影術具有下列優勢:1) 此技術不需催迫(stress test),即可篩檢出具有易感染遺傳特性的心肌組織或心肌基質特性已發生改變的患者,提早做預防處置;2)作為心律不整發生機制的診斷工具,用以輔助判斷最適合的介入治療方案;3) 可定位最佳心臟治療區域,如心導管電燒位置、標靶藥物或基因靶向等定位輔助;4)可輔助評估療效和長期預後追蹤等優點。
    Relation: 財團法人國家實驗研究院科技政策研究與資訊中心
    Appears in Collections:[Department of Biomedical Sciences and Engineering ] Research Project

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