Taiwan Institute of Chemical Engineers;Elsevier B.V
摘要:
摘要： •Adding limonene 3ml/l and irradiated with red light intensity 300lx enhanced both biomass and triterpenoid production.•Tangerine oil with red light was most effective for triterpenoid production.•Red light mitigates the inhibitory effect of monoterpenes and tangerine oil to mycelia. Improving cultivation techniques for the submerged fermentation of Antrodia cinnamomea is the most effective solution to address the growing market demand. However, low triterpenoids content is observed during submerged culture. The main purpose of this research was to investigate the effect of addition of monoterpenes and tangerine oil to the cultures of A. cinnamomea irradiated with red light for enhancing triterpenoids production. Experimental results suggested that xylose can replace glucose as a carbon source. Adding limonene 3ml/l and irradiated with red light intensity 300lx enhanced both biomass and triterpenoid production. The triterpenoid production increased to 46.07mg/g DW in shake flask cultures. Adding tangerine oil 3ml/l and irradiated with red light intensity 300lx proved to be the most effective in enhancing triterpenoid production to 67.69mg/g DW. Results indicated that the red light alleviated the inhibitory effect of monoterpenes and tangerine oil to mycelia. The process is industrially feasible as upscaling in a 2.5l airlift bioreactor improved both the biomass and triterpenoids content. [Display omitted] 出版者： Elsevier B.V 出版日期： 2016-10 出處： Journal of the Taiwan Institute of Chemical Engineers, 2016-10, Vol.67, p.140-147 資源來源： Elsevier ScienceDirect Journals Complete 版權： 2016 Taiwan Institute of Chemical Engineers 識別號： ISSN: 1876-1070 識別號： EISSN: 1876-1089 識別號： DOI: 10.1016/j.jtice.2016.08.023
