Using regression models to determine the poroelastic properties of cartilage

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題名:	Using regression models to determine the poroelastic properties of cartilage
作者:	鍾禎元;Chung, Chen-Yuan;Mansour, Joseph M.
貢獻者:	工學院機械工程學系
關鍵詞:	Biomechanical Phenomena;Boundary conditions;Cartilage, Articular - physiology;Computer Simulation;Elasticity - physiology;Finite Element Analysis;Humans;Linear Models;Linear regression;Models, Biological;Permeability;Physical Medicine and Rehabilitation;Poroelasticity;Porosity;Stress relaxation;Stress, Mechanical;Studies;Transversely isotropic
日期:	2013-07-26
上傳時間:	2026-04-23 15:32:23 (UTC+8)
出版者:	Elsevier Ltd.;United States: Elsevier Ltd
摘要:	摘要： The feasibility of determining biphasic material properties using regression models was investigated. A transversely isotropic poroelastic finite element model of stress relaxation was developed and validated against known results. This model was then used to simulate load intensity for a wide range of material properties. Linear regression equations for load intensity as a function of the five independent material properties were then developed for nine time points (131, 205, 304, 390, 500, 619, 700, 800, and 1000s) during relaxation. These equations illustrate the effect of individual material property on the stress in the time history. The equations at the first four time points, as well as one at a later time (five equations) could be solved for the five unknown material properties given computed values of the load intensity. Results showed that four of the five material properties could be estimated from the regression equations to within 9% of the values used in simulation if time points up to 1000s are included in the set of equations. However, reasonable estimates of the out of plane Poisson's ratio could not be found. Although all regression equations depended on permeability, suggesting that true equilibrium was not realized at 1000s of simulation, it was possible to estimate material properties to within 10% of the expected values using equations that included data up to 800s. This suggests that credible estimates of most material properties can be obtained from tests that are not run to equilibrium, which is typically several thousand seconds. 其他題名： J Biomech 出版者： United States: Elsevier Ltd 出版日期： 2013-07-26 出處： Journal of biomechanics, 2013-07, Vol.46 (11), p.1921-1927 版權： 2013 Elsevier Ltd 版權： Elsevier Ltd 版權： Copyright © 2013 Elsevier Ltd. All rights reserved. 版權： Copyright Elsevier Limited 2013 版權： 2013 Elsevier Ltd. All rights reserved. 2013 識別號： ISSN: 0021-9290 識別號： ISSN: 1873-2380 識別號： EISSN: 1873-2380 識別號： DOI: 10.1016/j.jbiomech.2013.05.028 識別號： PMID: 23796400
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