| DC 欄位 |
值 |
語言 |
| DC.contributor | 化學學系 | zh_TW |
| DC.creator | 陳鉦昇 | zh_TW |
| DC.creator | Cheng-Sheng Chen | en_US |
| dc.date.accessioned | 2014-8-28T07:39:07Z | |
| dc.date.available | 2014-8-28T07:39:07Z | |
| dc.date.issued | 2014 | |
| dc.identifier.uri | http://ir.lib.ncu.edu.tw:444/thesis/view_etd.asp?URN=101223041 | |
| dc.contributor.department | 化學學系 | zh_TW |
| DC.description | 國立中央大學 | zh_TW |
| DC.description | National Central University | en_US |
| dc.description.abstract | 本篇論文發展一新方法：利用氯化鈀作為催化劑，以含苯甲酸之烯化合物作為起始物，進行烯烴異構化反應。且反應後的碳-碳雙鍵為單一E-from結構，產率達92%。應用此反應，以掌性雙烯雙醇化合物5作為起始物，合成天然物Aigialomycin D之差向異構物5′-epi-Aigialomycin D (1)。其中碳-碳鍵的生成以交叉置換反應 (Cross Metathesis) 完成，大環內酯以Yamaguchi內酯化反應建構。 | zh_TW |
| dc.description.abstract | A novel palladium-catalyzed isomerization of alkenylbenzoic acid has been developed. This methodology could be applied to synthesis 5′-epi-Aigialomycin D by using chiral dienediol 5 as the starting material. The key reactions included cross metathesis (CM) and Yamaguchi lactonization. | en_US |
| DC.subject | 異構化 | zh_TW |
| DC.subject | 鈀金屬催化 | zh_TW |
| DC.subject | 環內酯 | zh_TW |
| DC.subject | Aigialmycin D | en_US |
| DC.subject | isomerization | en_US |
| DC.subject | resorcyclic lactone | en_US |
| DC.title | 鈀催化含苯甲酸之烯化合物異構化反應並合成5′-epi-Aigialomycin D | zh_TW |
| dc.language.iso | zh-TW | zh-TW |
| DC.type | 博碩士論文 | zh_TW |
| DC.type | thesis | en_US |
| DC.publisher | National Central University | en_US |