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In oriental culture, mushrooms has been used as health foods and home remedies for thousands of years. In several edible mushrooms, Agaricus blazei Murill was considered one of the most important edible and medicinal mushrooms native from Brazei. We also called it Agaricus brasiliensis. Many studies had proved that the Agaricus blazei Murill have strong immunomodulatory and health care functions, such as immune-enhancement, oxidation resistance, lower blood lipids et al. Recently, Agaricus blazei Murill is fascinating natural source for obtaining bioactive materials such as polysaccharides, beta-D-glucan and ergosterol. Among these chemical components, its polysaccharides with antitumor activity have attracted most attention.
Therefore, the yields and functionality of bioactive properties produced by liquid fermentation are highly depend on the culture conditions and environment parameters, such as pH, medium compositions, culture temperature and aeration rate et al.
Culture temperature is the one of the most important parameters influencing the production of bioactive properties and the cell growth. So, in my research I choose two different fruiting time of Agaricus blazei Murill to study on the effect of culture temperature ranging from 20℃ to 40℃ on cell growth, production of bioactive polysaccharides and beta-D-glucan. Agaricus blazei Murill were evaluated via five culture temperatures in step of 5℃ in a liquid fermentation, in order to optimize liquid fermentation condition of Agaricus blazei Murill for highest amount of biomass, bioactive polysaccharides and beta-D-glucan production and to compare what different between two strains of Agaricus blazei Murill. According to the results, use the two-stage temperature to increase the production of beta-D-glucan content. | en_US |