| dc.description.abstract | In recent years, the advancement of science and technology has improved the level of human life.In order to maintain a good quality of life, it has also promoted the development of biotechnology and medical care,and made the biomedical science become a hot topic of research in the world.
To get the reliable signals from sparse single molecules in low concentration is the final goal of biosensors. In order to achieve it, in this study, under the principle of surface-enhanced resonance raman scattering(SERRS), InGaN quantum wells with high refractive index and high chemical stability on the semiconductor are deposited on ZnO nanorod which are epitaxial grown in low-cost way by MOCVD and it has a rough and nanopyramid-like surface with Au nanoparticles. And the Rhodamine6G a kind of fluorescent molecules are used as the analyte to analyze the application and potential of this unique 2D nanostructured substrate in biosensing.
The performance of R6G on the Raman spectrum reflects the enormous advantage of this unique structure. In addition to an EF value is high to 106 and limit of detection is down to
10-12 that is very low concentration of molecular, it also has a large area with the “hot spots” which are evenly distributed on surface, and low-cost of production, the simple and convenient of measurement, the stability of enhancement , the small, thin and light of the volume, there is great potential in biosensing and single molecule detection.
| en_US |