dc.description.abstract | Organosilicons for surface modification are emphasized for their ease of rapid preparation high availability, and effective modification of different interfacial. The commercial silane 3- (Trimethoxysilyl)propyl methacrylate (TMSPMA) has been widely used in the preparation of organic/inorganic hybrid materials. The silane agent has a trialkoxysilyl group, which reacts with hydroxyl groups on the metal surface and then form Si-O-metal covalent bonds. The methacrylic functional group of the silane agent was firstly polymerized with the other monomers to form a silane-containing functional ploymer. However, TMSPMA is easy to be hydrolyzed, making it inconvenient to store, and requiring an anhydrous solvent for coating. The constrains of conventional metharylic silanes lead to troublesome for industrial implementations. In this study, we synthesized methylacrylate silatrane (MAST) with a tricyclic caged structure and a transannular N → Si dative bond, which shows excellent chemical stability in the presence of water. MAST was applied to co-polymerize with bio-inspired zwitterionic 2-Methacryloyloxyethyl phosphorylcholine (MPC) monomer for antifouling modification on silica surfaces. The chemical structure of the developed MAST was characterized by using nuclear magnetic resonance spectroscopy (NMR), mass spectrometry (MS). The chemical stability in presence of water, molecular orientation, roughness, the film thickness and wettability of methacrylated silatranes were compared with commercially available TMSPMA by using NMR, X-ray photoelectron spectroscopy (XPS), atomic force microscope (AFM), ellipsometry, water contact angle, respectively. In addition, an antifouling zwitterionic MPC monomer was employed for constructing a functional copolymer with MAST by conventional free polymerization for surface deposition on silicon. The functionalities of coatings were verified by treating with hydrogel attachment, protein fouling test, and bacterial adsorption. The thesis contributes the advance of silane chemistry by developing a robust and stable acrylic organolsilane for reproducible, orderly oriented, well defined polymeric coating with an aim for controlled silanization. | en_US |