| dc.description.abstract | Compared to traditional batch reactors, flow reactors offer several notable advantages, including uniform mixing, high efficiency of heat and mass transfer, ease of controlling residence time, and high reproducibility. Therefore, flow reactor systems can rapidly determine optimal reaction conditions through appropriate selection of reaction parameters and can be applied to large-scale production to increase production efficiency.
In this study, a fluorinated ethylene propylene (FEP) transparent tubing was utilized as a continuous reactor, with green LED light serving as the light source for photopolymerization. Additionally, we utilized a pump controller to automatically adjust various reaction parameters, such as residence time, monomer concentration, and photocatalyst/monomer ratio, and an automatic sample collector to sort products. Furthermore, this tubular continuous reactor, due to its simple design and low cost, is suitable for scaling up production and reducing synthesis costs. It can also be used for high-throughput synthesis to screen copolymer compositions rapidly, thereby enabling the rapid synthesis and analysis of a wide range of polymers. In this experiment, acrylamide showed better reactivity and conversion. Therefore, we synthesized a copolymer with a molecular weight of approximately 25,000 g/mole based on sulfobetaine acrylamide (SBAA) and acryloylglycine (AG). Sulfobetaine acrylamide has the effect of antibacterial and antifouling. Acryloylglycine can be modified on the 316 stainless steel substrates through hydrogen bonding. The copolymers were identified using proton nuclear magnetic resonance (1H NMR) spectroscopy to determine their structures and conversion rates, followed by gel permeation chromatography (GPC) to confirm molecular weights under different conditions. Finally, we modified stainless steel substrates by grafting the copolymers, and their hydrophilicity was confirmed using a water contact angle measurement instrument. The surface composition of the coatings was verified using X-ray photoelectron spectroscopy (XPS) and attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR). Bacterial and protein attachment tests were conducted to assess the anti-fouling properties of the coatings. | en_US |