| dc.description.abstract | With the widespread adoption of contact lenses, the associated risks of ocular complications due to their inherent poor wettability present a significant challenge. Contact lenses, worn daily on the cornea, are susceptible to microbial invasion from the air or hands if not properly cleaned, leading to corneal inflammation, pain, and other damages. Therefore, contact lenses need antibacterial properties to maintain eye health. Dry eyes are the most common issue faced by contact lens wearers today, accompanied by deposits on the lenses (proteins and lipids from tears), which reduce visual contrast and cause discomfort, leading to shorter wear times.
To address these issues, we use polysaccharides to modify the surface of contact lenses. We aim to create durable, multilayer antibacterial films that enhance the interaction between the contact lens and the ocular surface by applying these polysaccharides. This modification is designed to introduce a more biocompatible and eye-friendly hydrophilic layer. Our research involves a comprehensive evaluation to assess the impact of polysaccharide modification on contact lenses, focusing on wettability, antibacterial efficacy, and resistance to protein adhesion.
In summary, contact lenses need antibacterial properties to maintain eye health and anti-protein deposition functionality to enhance wearer comfort. Our research aims to use polysaccharide surface modifications to provide better wettability, antibacterial properties, and resistance to protein adhesion, thereby comprehensively improving contact lenses′ performance and user experience. | en_US |