| DC 欄位 |
值 |
語言 |
| DC.contributor | 化學學系 | zh_TW |
| DC.creator | 陳俐如 | zh_TW |
| DC.creator | Li-ju Chen | en_US |
| dc.date.accessioned | 2008-1-24T07:39:07Z | |
| dc.date.available | 2008-1-24T07:39:07Z | |
| dc.date.issued | 2008 | |
| dc.identifier.uri | http://ir.lib.ncu.edu.tw:444/thesis/view_etd.asp?URN=942203037 | |
| dc.contributor.department | 化學學系 | zh_TW |
| DC.description | 國立中央大學 | zh_TW |
| DC.description | National Central University | en_US |
| dc.description.abstract | 在本篇論文中，我們利用掌性苯乙胺及其衍生物來控制7-氯-2-庚烯甲酯進行分子內Michael 加成反應時之非鏡像立體選擇性，並且也研究(R)- α-苯乙胺加成至不同官能基之Michael acceptor 時，包括酯類、酮類和Weinreb 醯胺，其非鏡像立體選擇性的差異。最後，並將其應用來合成天然物(－)-allosedridine 和(－)-2’’-epi-ethylnorlobelol。 | zh_TW |
| dc.description.abstract | In this thesis, we apply the chiral methylbenzylamine and their derivatives to control the diastereoselectivity of the methyl 7-chlorohept-2-enoate in intramolecular Michael addition reactions. And we also study the differences of the diastereoselectivity when (R)-α-ethylbenzylamine reacts with different Michael acceptors, including the ester, ketone and Weinreb amide. Finally, we apply this methodology to synthesize two natural products (－)-allosedridine and (－)-2’’-epi-ethylnorlobelol. | en_US |
| DC.subject | Michael加成反應 | zh_TW |
| DC.subject | 非鏡像立體選擇性 | zh_TW |
| DC.subject | (－)-2'-epi-Ethylnorlobelol | en_US |
| DC.subject | (－)-Allosedridine | en_US |
| DC.subject | diastereoselectivity | en_US |
| DC.subject | Michael addition | en_US |
| DC.title | 分子內Michael 加成反應之非鏡像立體選擇性探討與天然物(－)-Allosedridine 和 (－)-2’-epi-Ethylnorlobelol 之合成 | zh_TW |
| dc.language.iso | zh-TW | zh-TW |
| DC.title | Total Synthesis of (－)-Allosedridine and (－)-2’-epi-Ethylnorlobelol by Diastereoselective Intramolecular Michael Addition | en_US |
| DC.type | 博碩士論文 | zh_TW |
| DC.type | thesis | en_US |
| DC.publisher | National Central University | en_US |