摘要(英) |
3
Abstract
The overgrowth of Cutibacterium acnes (C. acnes), a commensal skin bacterium, has been
associated with the progression of acne vulgaris. Human skin and gut bacteria can produce
electricity by fermentation. Based on this electricity producing ability of bacteria we have tested to
check whether Staphylococcus epidermidis (S. epi) fermentation with Amylose can inhibit the
growth of C. acnes by producing electricity. We found that human gut and skin bacteria can
produce significantly higher electricity when the fermentation mediated by various prebiotics. We
have selected glucose and glycerol which are most common prebiotics for measuring the
production of electricity of bacteria from gut Lactobacillus rhamnosus (L. rhamnosus), Escherica
coli (E. coli), Klebseilla pneumoniae (K. pneumoniae) and bacteria from skin C. acnes, S. epi,
Staphylococcus aureus (S. aureus). We have tested 3 different prebiotics Glyceryl cocoate (PEG-
7), Alpha lactose monohydrate (ALM), Amylose (Amy) for measuring prebiotic mediated
production of electricity from S. epi. The Amylose mediated fermentation of S. epi has shown the
highest production of electricity. Our results demonstrated that S. epi can mediate fermentation of
Amylose to enhance its inhibitory effects on C. acnes growth by producing electicity in vivo and
in vitro.
Keywords: C. acnes, S. epi, L. rhamnosus, E. coli, K. pneumoniae, S. aureus, PEG-7, ALM, Amy |
參考文獻 |
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