重複性經顱磁刺激同步虛擬實境與生理監測用於失語症創新治療與評估

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高嘉君(Chia-Chun Kao) 查詢紙本館藏

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資訊工程學系

論文名稱

重複性經顱磁刺激同步虛擬實境與生理監測用於失語症創新治療與評估
(Synchronizing Repetitive Transcranial Magnetic Stimulation with Virtual Reality and Physiological Monitoring for Innovative Aphasia Treatment and Assessment)

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至系統瀏覽論文 (2026-7-31以後開放)

摘要(中)

失語症是一種語言障礙，通常由中風引起，影響全球數百萬人。本研究提出了一種創新的系統，結合重複性經顱磁刺激、虛擬實境和生理監測，用於失語症的治療和評估。本研究旨在評估rTMS與基於VR的語言訓練的協同效果，並使用生理數據作為輔助評估手段，以期通過rTMS刺激活化腦部同時，利用VR訓練加強並延續治療效果。共有24名參與者參與了本實驗，其中16名失語症患者隨機分配至實驗組和對照組A，8名健康受試者作為對照組B。研究開發了五個基於VR的模組，其中四個評估模組用於語言能力評估，一個介入模組用於語言能力提升。隨機對照試驗結果顯示，rTMS與VR結合在提高語言能力方面具有潛力，任務表現及生理數據驗證了治療效果，並提供了輔助評估的初步證據。這種方法旨在提供更全面有效的失語症治療，以期在未來實現更加個性化的智慧治療。

摘要(英)

Aphasia, a language disorder often caused by stroke, affects millions of people worldwide. This study proposes an innovative system integrating repetitive transcranial magnetic stimulation (rTMS), virtual reality (VR), and physiological monitoring for the treatment and assessment of aphasia. The aim is to evaluate the synergistic effects of combining rTMS with VR-based language training, using physiological data as an auxiliary assessment tool. It is expected that rTMS will activate brain regions, while VR training enhances and extends therapeutic effects. A total of 24 participants were involved in this experiment: 16 aphasia patients were randomly assigned to the experimental group and control group A, while 8 healthy participants formed control group B. Five VR-based modules were developed, with four assessment modules for evaluating language abilities and one intervention module for enhancing language skills. The randomized controlled trial results indicate that combining rTMS and VR has potential in improving language abilities. Task performance and physiological data provided validation and interpretation of therapeutic effects, as well as preliminary auxiliary assessment. This approach aims to offer a more comprehensive and effective treatment for aphasia, with the potential for more personalized intelligent therapy in the future.

關鍵字(中)

★ 失語症
★ 重複性經顱磁刺激
★ 虛擬實境
★ 機器學習
★ 多模態融合
★ 生理監測

關鍵字(英)

★ Aphasia
★ Repetitive Transcranial Magnetic Stimulation
★ Virtual Reality
★ Machine Learning
★ Multimodal Fusion
★ Physiological Monitoring

論文目次

摘要 i
Abstract ii
致謝 iii
Table of Contents iv
List of Figures v
List of Tables vi
List of Abbreviations viii
I. Introduction 1
II. Related Works 6
III. Methodology 10
IV. Results 23
V. Discussions 48
VI. Conclusion and Future Works 52
Reference 54

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指導教授

葉士青吳曉光

審核日期

2024-8-2

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