Application of Steric-Mass Action model to triblock copolymer as a displacer in ion-exchange displacement chromatography

NCU Institutional Repository > 工學院 > 化學工程與材料工程研究所 > 期刊論文 > Item 987654321/26456

請使用永久網址來引用或連結此文件: http://ir.lib.ncu.edu.tw/handle/987654321/26456

題名:	Application of Steric-Mass Action model to triblock copolymer as a displacer in ion-exchange displacement chromatography
作者:	Chen,WY;Dai,KC;Ho,KC;Lin,FY;Huang,HM
貢獻者:	化學工程與材料工程學系
關鍵詞:	INDUCED SALT GRADIENTS;METHACRYLIC POLYAMPHOLYTES;DEXTRAN SULFATE;ABC TRIBLOCK;PROTEINS;AFFINITY
日期:	1999
上傳時間:	2010-06-29 17:28:29 (UTC+8)
出版者:	中央大學
摘要:	This study explores the feasibility of using triblock copolymer polyampholytes as a displacer to separate beta-lactoglobulin A and B isoforms by anion exchange displacement chromatography. The displacers used herein are methacrylic polyampholytes: A(8)M(12)B(12), A(16)M(12)B(12) and A(16)M(24)B(24), where A is methacrylic acid, B is 2-(dimethylamino)ethyl methacrylate, and M is methyl methacrylate. In addition, the steric factor, characteristic charges and binding equilibrium constant with the ion exchanger gel of the triblock copolymer are measured and discussed with the structure and solution behavior of the polyampholytes. With the Steric-Mass Action (SMA) model of ion-exchange displacement chromatography, the elution and displacement line can be constructed for the system. Moreover, the behavior of elution and displacement line is qualitatively discussed and successfully proven.
關聯:	JOURNAL OF THE CHINESE INSTITUTE OF CHEMICAL ENGINEERS
顯示於類別:	[化學工程與材料工程研究所] 期刊論文

文件中的檔案:

檔案	描述	大小	格式	瀏覽次數
index.html		0Kb	HTML	486	檢視/開啟

在NCUIR中所有的資料項目都受到原著作權保護.

社群 sharing