English  |  正體中文  |  简体中文  |  Items with full text/Total items : 74010/74010 (100%)
Visitors : 24088176      Online Users : 466
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version

    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/66775

    Title: 組成成分與溫度對生物膜彈性性質的影響;Composition and temperature effects on the elastic properties of membranes
    Authors: 邱忠憲;Chiu,Jhong-Sian
    Contributors: 生物物理研究所
    Keywords: 生物膜;抗菌生態;脂質分子
    Date: 2015-01-23
    Issue Date: 2015-03-16 15:12:21 (UTC+8)
    Publisher: 國立中央大學
    Abstract: 生物膜在細胞中扮演非常重要的角色,除了保護著細胞,許多由細胞膜媒
    影響,我們利用 X 光繞射在不同溫度中測量不同脂質混合物的結構,進一步藉
    DOPE 形狀相同生物分子會使得自然曲率半徑不變,其餘與 DOPE 分子形狀不
    下降;最後蜂毒胜肽使得 DOPE 的六角型相態極為不易產生;在溫度上升時,
    不同的脂質混合物的自然曲率半徑都有了些微的下降。;Biological membranes play very important role for the cell. They not only protect
    the cell but also mediate the biological processes to maintain the activity of cell.
    Therefore, studying biological membranes is very important. In the past decades, a lot
    of membrane structure and membrane-mediated biological processes have been studied.
    However, most of the mechanisms of these biological processes are still the puzzles. In
    this report, we studied the elastic properties of membranes by biophysical method for
    further understanding these processes.
    Different types of cells have varied membrane composition of lipids. The lipid
    composition and temperature are able to affect the membrane-mediated biological
    processes. We used x-ray diffraction to determine the structure of membranes in
    different compositions as well as different temperatures. The elastic properties of
    membranes were extracted from X-ray data by changing the osmotic pressure. We
    should understand the biological processes more through the determination of the
    elastic properties of membranes.
    Consequently, we found different molecular shapes of the additives compare to
    DOPE cause the increase of intrinsic radius of curvature. The negative charged lipids
    decrease the intrinsic radius of curvature slightly. Melittin hold DOPE membranes in
    the lamellar phase instead of hexagonal phase. Finally, the intrinsic radii of curvature
    of all lipid mixtures decrease with temperature increasing.
    Appears in Collections:[生物物理研究所 ] 博碩士論文

    Files in This Item:

    File Description SizeFormat

    All items in NCUIR are protected by copyright, with all rights reserved.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback  - 隱私權政策聲明