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    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/70044


    Title: 探討與MAPK/ERK 訊息傳遞相關之新穎微型RNA 在訊息傳遞之調控及對黑色素瘤的作用;Exploration of Novel MAPK/ERK Related microRNAs in Regulation of MAPK/ERK Signaling Pathway and Their Functional Effects in Melanoma
    Authors: 馬念涵;呂仁
    Contributors: 系統生物與生物資訊研究所
    Keywords: 訊息傅遞路徑;_x000d_ 微型RNA;_x000d_ 腫瘤;_x000d_ 黑色素瘤;生物標記;Signaling transduction;Tumor progression;MAPK/ERK signaling;_x000d_ microRNA;melanoma;Biomarkers;基礎醫學;生物技術(醫)
    Date: 2016-03-29
    Issue Date: 2016-03-30 11:12:04 (UTC+8)
    Publisher: 科技部
    Abstract: 近來微型RNA (MicroRNAs or miRNAs)已被證明是轉錄後基因表現的主要調節者,微型 RNA表現不正常也影響許多疾病的產生。此外,在現今的研究中指出,比起傳統mRNA 表現為基礎架構來分辨癌症,微型RNA是為更有效率的分類依據。因此,微型RNA很有 機會成為未來新穎癌症的指標,及用於癌症治療。Mitogen-activated protein kinase (MAPK/ERK) 訊息傳遞路徑的活化與許多細胞癌化息息相關。例如高達百分之六十以上 在黑色素瘤細胞中發現有MAPK/ERK訊息傳遞;MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of gene expression in human. Recent studies reported that miRNAs profiles are more effective in cancer classification than mRNA profiles, indicating that miRNAs would be better and nov;研究期間:10408~10507
    Relation: 財團法人國家實驗研究院科技政策研究與資訊中心
    Appears in Collections:[系統生物與生物資訊研究所] 研究計畫

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