隨著智慧型手機普及與民眾對健康的重視,現今已有超過10萬個醫療健康App可供使用,在取代性高的App市場中如何提高使用者滿意度與持續使用率成為重要研究議題。本研究以科技接受模型為理論基礎,探討認知性變數(有用性、易用性)與設計型變數(設計美觀性、回應時間、資訊品質)對大學生使用醫療App滿意度與使用意圖的影響。本研究使用實際操作的方式,讓使用者操作兩種App,分別是功能導向型和醫療資訊型App,接著再以台灣某大學學生為研究對象進行問卷調查,在三個月的研究時間中發放共計150份問卷並全數有效回收,資料分析方法採用多元迴歸模型。結果顯示(1)對功能導向型App而言,設計美觀性和回應時間各以正負向關係顯著影響使用者滿意度(p<0.05),進而影響再使用意圖;(2)對醫療資訊型App而言,資訊品質對使用者滿意度有最顯著的影響效果,再影響到再使用意圖;(3)認知性變數對設計型變數影響使用者滿意度的關係有中介效果。本研究成果可協助相關業者設計適合目標客群的醫療保健App。;With the popularity of smart phone and an increasing concern for health and wellness, there are currently more than 100 thousand health-related mobile Apps available. How to raise user’s satisfaction and utilization in the highly replaceable App market becomes an important research area. This study uses technology acceptance model (TAM) to investigate how cognitive factors (perceived ease of use and perceived usefulness) and design factors (aesthetics, response time and information quality) affect college students’ satisfaction and intention on using health-related Apps. Two types of Apps, function-oriented and information-oriented, were examined in this study. A total of 150 valid questionnaires were collected from the students at a university of northern Taiwan during a three months period. Multi- regression model was used to analyze the data. The results show that (1) for function-oriented Apps, aesthetics and response time have significant effect on user satisfaction (p<0.05). User satisfaction has significant effect on continuance usage intention. (2) for information-oriented Apps, information quality has the most significant effect on user satisfaction(p<0.05). (3) There is mediating effect of cognitive factors on the relationship of design factors and user satisfaction. Overall, the results provide important references for Apps companies to develop appropriate health-related Apps for customers.