台灣科學園區的設立是建立在以技術密集的高科技工業，推動台灣整體創新發展為 前提下而成立，因此，台灣科學園區大多以電子業出口導向之廠商為主；然而，近年來 全球經濟陷入低迷，重創許多出口導向型國家，因此，本研究欲針對台灣電子上市上櫃 公司，探討2010-2016年台灣科學園區近年來園區內外廠商，在研發創新與生產績效上 之比較。此外，隨著全球化經濟與知識技術的迅速擴散，進一步探討園區內外廠商在專 利發明上，是否有國際合作之表現。 實證結果顯示，園區內廠商在研發專利上，對於總要素生產力之影響為正向顯著， 尤其是在專利表現上，園區內廠商更是明顯優於園區外，表示園區內廠商在研發創新上 仍舊具有優勢，且對於企業的總要素生產力也有十足的影響；此外，考量了專利研發國 際合作上之評估，對於園區內的總要素生產力同樣有高度正向顯著之影響，但園區外廠 商則為負向顯著，而這有可能是因為專利畢竟屬於各國企業的獨家技術，相對來說較為 隱私，因而園區外廠商在專利研發國際合作才可能呈現負相關，然而，科學園區內或許 存在著一些保護或合作機制，因而園區內廠商則呈現正向顯著關係。;The establishment of the Taiwan Science Park is based on the premise of intensive high-tech industries and the promotion of Taiwan’s overall innovation and development. According to the present situation, most of the Taiwan Science Parks are mainly electronics-oriented export-oriented manufacturers. However, the global economy has been trapped in recent years. Many export-oriented countries were heavily damaged. Therefore, this study is intended to target Taiwan’s e-listed companies to explore the comparison between R&D innovation and production performance of Taiwan’s in and outside Science Park manufacturers from 2010 to 2016. In addition, with the rapid diffusion of globalized economy and technology, it is further explored whether there are international cooperation in the invention of patents in and outside the park’s manufacturers. The empirical results show that in the R&D and patents, the manufacturers in the park have a positive effect on the total factor productivity. Especially in the performance of patents, the manufacturers in the park are obviously better than the outside of the park. It means that the companies in the park still have advantages in research and innovation, and they also have a full impact on the total factor productivity of the company. In addition, considering the assessment of international cooperation in patent research and development, it also has a highly positive and significant effect on the total factor productivity in the park, but the manufacturers outside the park are negative. This may be because patents are exclusive technologies of companies in all countries and are relatively private. Therefore, the manufacturers outside the park may have negative correlations in international cooperation in patent research and development. However, there may be some protection or cooperation mechanisms in the science parks, so that the firms in the park are showing a positive relationship.