傳統的雙光子光致聚合(Two-photon Phtotopolymerization)微製造技術，通常藉由體素與體素緊密排列的方式來形成一層的二維圖形，並且再藉由積層製造的方法來製作出三維結構，其體素的空間解析度可達到次微米等級。然而在製作次毫米尺寸以上之結構時，如此高的空間解析度勢必要犧牲製作時間，一但製造時間拉長，製造失敗的風險也將大幅提升。對此，本研究建立一套快速製造且結構完整的TPP微製造系統。透過連續掃描的方式，並且儘對於輪廓表面進行曝光，以利提升整提製作效率。再透過運用在熔融沉積(Fused Deposition Modeling, FDM)的內部支撐加強模型結構的概念，來運用在TPP微製造中，並且成功製作次毫米結構。於本研究中，首先透過上昇掃描法來建立出雷射功率及平台移動速度對於線徑尺寸影響之資料庫。接著透過簡單外型來找尋出製作三維結構時的最佳參數。最後則是成功製作出次毫米尺寸的人體跟骨模型，並且比較有無內部支撐結構的差異及製造時間。;The conventional Two-photon Photopolymerization(TPP) micro-fabrication technology usually forms a two-dimensional patterns by closely stacking voxels and voxels, and then creates a three-dimensional structure by additive manufacturing. The spatial resolution of voxels can reach sub-micro level. However, it must be a trade off between high spatial resolution and total fabrication time when making a structure with a sub-millimeter size or more. Once the fabrication time longer, the risk of manufacturing failure will be greatly increased. To improve overall fabricating time, this study fabricates sub-millimeter structures by continuous scanning method and exposing only on the contour of the structure. And then, this study applies the inner support method previously applied to Fused Deposition Modeling (FDM) to TPP microfabrication, and the submillimeter structure was successfully fabricated. In this study, the ascending method is first used to establish a database of influence of laser power and scanning speed on the line size. And then, find an optimal parameter by fabricating a simple model. Finally, the human calcaneus model with sub-millimeter size was successfully produced, and then comparing structural differences and fabricating time with or without inner support.
