摘要： The vinylalumination of α-substituted aldehydes gave anti - and syn -adducts with moderate diastereoselectivity. The diastereomeric ratio was inverted by the addition of lithium or sodium perchlorates. Thus, both anti - and syn -adducts were isolated and transformed into the biologically active conduritols, pericosine B and C, respectively. Formal synthesis of pericosine A was achieved with the anti -adduct. The rationales for the different diastereoselectivity are discussed. The vinylalumination of α-substituted aldehydes gave anti - and syn -adducts with moderate diastereoselectivity. 出版日期： 2013-11-19 資源來源： Royal Society of Chemistry 識別號： EISSN: 2046-2069 識別號： DOI: 10.1039/c3ra45871g
