Stem Cell Therapy for Treatment of Ocular Disorders

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題名:	Stem Cell Therapy for Treatment of Ocular Disorders
作者:	樋口亞紺;Kumar, S. Suresh;Umezawa, Akihiro;Munusamy, Murugan A.;Alarfaj, Abdullah A.;Murugan, Kadarkarai;Higuchi, Akon;Mok, Pooi-Ling;Syed, Sakinah;Sivan, Padma Priya;Hamat, Rukman Awang
貢獻者:	工學院化學工程與材料工程學系
關鍵詞:	Colleges & universities;Cytokines;Diabetes;Diabetic retinopathy;Eye diseases;Gene expression;Genetic aspects;Genetic transcription;Grants;Growth factors;Hypoxia;Ionizing radiation;Medical research;Medicine, Experimental;Ophthalmology;Retina;Review;Science;Stem cells;Transplantation;Zoology
日期:	2016-01-01
上傳時間:	2026-04-21 14:46:39 (UTC+8)
出版者:	Hindawi Publishing Corporation;Cairo, Egypt: Hindawi Publishing Corporation
摘要:	摘要： Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow conventional treatments have shifted search to a new form of therapy using stem cells. Stem cell progenitors play a major role in replenishing degenerated cells despite being present in low quantity and quiescence in our body. Unlike other tissues and cells, regeneration of new optic cells responsible for visual function is rarely observed. Understanding the transcription factors and genes responsible for optic cells development will assist scientists in formulating a strategy to activate and direct stem cells renewal and differentiation. We review the processes of human eye development and address the strategies that have been exploited in an effort to regain visual function in the preclinical and clinical state. The update of clinical findings of patients receiving stem cell treatment is also presented. 其他題名： Stem Cells Int 出版者： Cairo, Egypt: Hindawi Publishing Corporation 出版日期： 2016-01-01 出處： Stem Cells International, 2016-01, Vol.2016 (2016), p.1-18 資源來源： Chinese Electronic Periodical Services (CEPS) 版權： Copyright © 2016 Padma Priya Sivan et al. 版權： COPYRIGHT 2016 John Wiley & Sons, Inc. 版權： Copyright © 2016 Padma Priya Sivan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 版權： Copyright © 2016 Padma Priya Sivan et al. 2016 識別號： ISSN: 1687-966X 識別號： ISSN: 1687-9678 識別號： EISSN: 1687-9678 識別號： DOI: 10.1155/2016/8304879 識別號： PMID: 27293447
顯示於類別:	[化學工程與材料工程學系 ] 期刊論文

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