English  |  正體中文  |  简体中文  |  Items with full text/Total items : 70585/70585 (100%)
Visitors : 23138445      Online Users : 501
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/79486


    Title: 探討miR-567在黑色素細胞瘤中的調控機制;Study of the mechanism of miR-567 in melanoma
    Authors: 黃昱齊;Huang, Yu Chi
    Contributors: 系統生物與生物資訊研究所
    Keywords: 微型核糖核酸;黑色素細胞瘤;miR-567;melanoma
    Date: 2019-01-21
    Issue Date: 2019-04-02 14:30:51 (UTC+8)
    Publisher: 國立中央大學
    Abstract: 過去實驗室致力於探討Mitogen-Activated Protein Kinases/ Extracellular signal-Regulated Kinase (MAPK)訊息傳導路徑相關之微型核糖核酸 (miRNA)。在目前已知此訊息傳導路徑因突變而過度活化的黑色素細胞瘤 (melanoma) 中,發現諸多miRNA的過量表現 (overexpression) 均具有影響癌症相關細胞功能性能力,如增生(Proliferation)、遷移/侵襲 (Migration/Invasion)、凋亡 (Apoptosis),認為此群miRNA具有癌症抑制基因(Tumor suppressor gene)之特質,並藉由抑制黑色素細胞瘤中可能產生預後不良的風險因子以及影響諸多與癌症進展相關之重要基因,希望將來成為有潛力的標靶治療手段。;We dedicated to investigating Mitogen-Activated Protein Kinases/ Extracellular signal-Regulated Kinase (MAPK) pathway-associated miRNAs in our previous study. While these miRNAs are overexpressed, it could suppress the multiple functional assays related to cancer development, such as proliferation, migration, invasion, and apoptosis in melanoma which harbored the mutation(s) to make MAPK pathway active. We hope that these miRNAs play the meaningful role as tumor suppressors and they could become the promising RNA interference drug against the specific cancer.
    Appears in Collections:[系統生物與生物資訊研究所] 博碩士論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML112View/Open


    All items in NCUIR are protected by copyright, with all rights reserved.

    社群 sharing

    ::: Copyright National Central University. | 國立中央大學圖書館版權所有 | 收藏本站 | 設為首頁 | 最佳瀏覽畫面: 1024*768 | 建站日期:8-24-2009 :::
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback  - 隱私權政策聲明