卡拉膠是一種常用於食品水凝膠和藥物載體的線性、帶電多醣類。在區分氫鍵和陽離子橋兩種交聯的機制後，這項研究提出了一種新穎且簡便的方法，可在室溫下輕易地獲得能形成膠囊和自立薄膜的卡拉膠水凝膠。首先，透過氫鍵的作用可以形成弱凝膠，然後通過引入陽離子橋將其轉化為強凝膠。因此，可以將弱凝膠作為可生物降解的3D打印材料，通過將其注入含有特定陽離子的支撐介質中來製造不同的3D結構。當卡拉膠的濃度較低時，凝膠無法形成。但在陽離子橋的作用下，微米級的微凝膠仍然可以自發形成，而透過純氫鍵無法自然形成微凝膠。卡拉膠微凝膠的分散液展現出降伏應力和黏彈特性。經過離心後，增濃後的分散液展現了自我修復能力，其可作為3D列印的支撐介質。;Carrageenan is a linear, charged polysaccharide that is commonly used as food hydrocolloids and drug carriers. After differentiating the gelling mechanisms of hydrogen bond and cation-bridge, this study presents a novel and facile method for obtaining carrageenan hydrogel that can be easily shaped into capsules and free-standing films at room temperature. Initially, a weak gel based solely on hydrogen bonds is developed, which can subsequently be transformed into a strong gel by introducing cation bridges. Therefore, the weak gel can be served as biodegradable 3D printing ink for producing structures by injecting it into a supporting medium containing specific cations. When the carrageenan concentration is low, the bulk gel fails to form. However, the micron-sized microgel can still form spontaneously due to cation-bridges, rather than hydrogen bonds. The dispersion of carrageenan microgels shows both yield stress and viscoelasticity. Upon centrifugation, the concentrated dispersion displays self-healing ability and can serve as a supporting medium for 3D printing.
