Investigation of posterior parietal cortex visuospatial control over processing in near and far space using  transcranial magnetic stimulation

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题名:	Investigation of posterior parietal cortex visuospatial control over processing in near and far space using transcranial magnetic stimulation
作者:	馬英傑;Mahayana,Indra Tri
贡献者:	認知與神經科學研究所
关键词:	視覺空間注意力;跨顱磁刺激儀;頂葉皮質;遠近空間;視覺空間忽略症;visuospatial attention;transcranial magnetic stimulation;posterior parietal cortex;far space;near space;visuospatial neglect
日期:	2014-06-25
上传时间:	2014-08-11 18:42:43 (UTC+8)
出版者:	國立中央大學
摘要:	人類大腦使用視覺空間注意力的能力來確認環境中視覺項目的位置。正常大腦的生理特性可以解釋各種行為現象，包含:個人空間、在有害的視覺刺激接近時的退避反應、或是迴避障礙。視覺空間辨識障礙的病人，普遍是頂葉受到損傷所造成的，病人通常會無法辨識和探索出現在對側空間的視覺刺激，此現象稱為視覺空間忽略症。探討頂葉皮質是如何調控視覺空間注意力，有助於了解正常大腦功能的理論基礎。因此，我們使用跨顱磁刺激儀(TMS)比較受試者的神經活動在有無受到干擾狀況下的行為表現，來探討大腦與行為之間的關聯性。本論文主要想探討視覺空間注意力在遠近距離的控制中，頂葉皮質所扮演的角色。遠近距離的辨識是由不同的視覺注意力神經機制所負責，因此也是一個重要的研究議題。;The fundamental ability of the human brain to locate visual items in the environment depends on visuospatial attention. Normal physiological properties of the brain explain a range of behavioral phenomena including the personal space of humans, the withdrawal reaction to approaching harmful visual stimuli, or avoidance of obstacles. A patient with visuospatial deficits, commonly as a result of parietal damage, experiences failure to acknowledge or explore stimuli toward the contralesional side of space, a phenomenon called visuospatial neglect. Research and investigation of how the parietal cortex controls visuospatial attention may contribute to the theoretical basis of healthy brain function. Hence, using transcranial magnetic stimulation (TMS) we can investigate the relationship between brain and behavior under controlled experimental conditions when comparing behavioral performance with and without local neural activity disruption. This thesis investigated parietal cortex function in visuospatial attention control in near and far space, coding of which is comprised of different neural mechanisms of visual attention and which will be important to investigate further.
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