以肌醇(myo-inositol)作為起始物，與同時作為保護基及掌性輔助劑的右旋樟腦(D-camphor)反應得到單一的非鏡像異構物56，經由選擇性去氧、以疊氮化鈉(sodium azide)作為親核試劑進行SN2反應生成碳氮鍵、Staudinger還原反應等步驟，得到其關鍵中心脫氧胺基鯊肌醇(2-deoxy-scyllo-inosamine)此種結構，最後再經由一系列反應得到Nabscessin A及Nabscessin B。;Nabscessin A and Nabscessin B were prepared from commercial available myo-inositol. Treating myo-inositol with protective reagent D- camphor, serving as chiral auxiliary simultaneously, got the diastereomeric pure compound 56. Subsequent transformatios, including selective deoxygenation, amino group formation, etc, provided the key 2-deoxy-scyllo-inosamine core. Finally we completed the synthesis through a series of reaction.
