本研究的目的是驗證在醫療行業的賦權領導對安全行為的影響,同時驗證知識分享和安全氣候的中介作用,我們採取了分層線性模型為研究框架來執行跨層次的分析。研究區分為個人層次與組織層次,個人層次為知識分享與安全行為;組織層次為賦權領導與安全氣候,可以有效且精確評估影響安全行為的變異。研究結果發現賦權領導是安全行為先決條件,特別是當領導者屬於賦權領導者,他們將對員工產生遵守安全步驟和安全要求。此外我們證實知識分享是賦權領導和安全行為之間的重要中介變項。賦權領導者授予員工參與決策的制定,鼓勵團隊成員共同解決問題,團隊成員間共同分享知識,而提升團隊成員知識分享的行為,進而改變員工對安全參與的積極性,增加成員對於安全行為的遵從。同時我們也驗證了安全氣候的中介作用。當領導者採用賦權領導,他們可創造良好的安全氣候,來促進安全行為。;This study aimed to validate the influence of empowering leadership on safety behavior in the medical industry and examine the mediating effects of knowledge sharing and safety culture. We adopted a hierarchical linear model to perform a cross-hierarchy analysis on the entire research framework. We examined knowledge sharing and safety behavior on the individual level and examined empowering leadership and safety culture on the organizational level. The findings revealed that empowering leadership is a prerequisite of safety behavior, particularly when leaders are empowering leaders. Such leaders formulate and comply with safety procedures and requirements and enhance safety participation. We validated that knowledge sharing is a key mediator between empowering leadership and safety behavior. Empowering leaders empower employees to participate in decision making and encourage them to resolve problems together and share knowledge, thereby enhancing their knowledge sharing behavior, safety participation willingness, and safety compliance. We also validated the mediating effects of safety culture. Leaders influence employees’ safety behavior through safety culture. When leaders adopt empowering leadership, they create favorable safety culture, which promote safety behavior.